Biological evaluations and spectroscopic characterizations of 3-(4-ethoxyphenyl)-2-methylacrylate based organotin(IV) carboxylates derivatives期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Biological evaluations and spectroscopic characterizations of 3-(4-ethoxyphenyl)-2-methylacrylate based organotin(IV) carboxylates derivatives

Authors:	Tariq M. Sirajuddin M. Ali S. Khalid N. Shah N. A.

Affiliation:	1.Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, 60000, Pakistan ;2.Department of Chemistry, University of Science and Technology, Bannu, 28100, Pakistan ;3.Department of Chemistry, Quaid-i-Azam University, Islamabad, 45320, Pakistan ;4.Chemistry Division, Pakistan Institute of Nuclear Science and Technology, P. O. Nilore, Islamabad, Pakistan ;5.Department of Biosciences, COMSATS Institute of Information Technology, Islamabad, Pakistan ;

Abstract:	Six new organotin(IV) carboxylates, [Me₂SnL₂] (1), [n-Bu₂SnL₂] (2), [n-Oct₂SnL₂] (3), [Me₃SnL] (4), [n-Bu₃SnL] (5) and [Ph₃SnL] (6), where L = 3-(4-ethoxyphenyl)-2-methylacrylate, have been synthesized and characterized by FT-IR, NMR spectroscopy and elemental analyses. The synthesized compounds were tested for in vitro antibacterial and antifungal activities. The complexes 4–6 demonstrated higher activity than the complexes 1–3. UV-Vis absorption spectroscopy indicated that the ligand and its complexes interacted with DNA via partial intercalation as well as minor groove binding.

Keywords:
本文献已被 SpringerLink 等数据库收录！