Palladium-catalyzed beta-allylation of 2,3-disubstituted indoles |
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| Authors: | Kagawa Natsuko Malerich Jeremiah P Rawal Viresh H |
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| Institution: | Department of Chemistry, University of Chicago, Chicago, IL 60637, USA. |
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| Abstract: | Given the prevalence of the indole nucleus in biologically active compounds, the direct C3-functionalization of 2,3-disubstituted indoles represents an important problem. Described is a general, high-yielding method for the palladium-catalyzed beta-allylation of carba- and heterocycle fused indoles, including complex natural product substrates. |
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