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FeCl3-SiO2 as a reusable heterogeneous catalyst for the synthesis of 5-substituted 1H-tetrazoles via [2+3] cycloaddition of nitriles and sodium azide
Authors:Mahmoud Nasrollahzadeh  Yadollah Bayat  Saeed Moshaee
Institution:a Laboratory of Organic Chemistry, Moshashimi Company, Kardikola Industrial Region, PO Box 47571-54879, Babol, Iran
b Department of Chemistry, Malek-Ashtar University of Technology, Tehran, Iran
c Department of Organic Chemistry, Faculty of Chemistry, Bu Ali Sina University, Hamedan 6517838683, Iran
Abstract:An efficient method for the preparation of 5-substituted 1H-tetrazole derivatives is reported using FeCl3-SiO2 as an effective heterogeneous catalyst. This method has the advantages of high yields, simple methodology, and easy work-up. The catalyst can be recovered by simple filtration and reused delivering good yields.
Keywords:5-Substituted 1H-tetrazole  [3+2] Cycloaddition  Nitrile  FeCl3-SiO2  Heterogeneous catalyst
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