Terbium-sensitized fluorescence method for the determination of pazufloxacin mesilate and its application. |
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| Authors: | Shilv Chen Hongwu Ma Huichun Zhao Ruiqing Feng Linpei Jin |
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| Institution: | Department of Chemistry, Beijing Normal University, Beijing, PR, China. |
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| Abstract: | A simple, rapid and highly sensitive fluorometric method for the determination of pazufloxacin mesilate (PZFX) is described. It is based on the formation of the complex Tb(PZFX)2](3+), which shows the intensive characteristic bands of Tb3+. Optimum conditions for the determination were investigated. Under the optimum experimental condition, the fluorescence intensity responds linearly to the PZFX concentration in the range of 2.0 x 10(-8) - 5.0 x 10(-6) mol/l with a detection limit of 6.2 x 10(-9) mol/l. The method has been successfully applied to the determination of PZFX in urine and serum samples. |
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