Adsorption of proteins of the surfaces of modified silicas

Sorbents based on porous and nonporous varieties of silica containing chemisorbed primary amines, alcohols, amino-alcohols, amide groups, and phenyl radicals with different types of substituents in the surface layer have been synthesized. It has been established that, depending on the nature of the modifying layer, electrostatic and hydrophobic interactions make the principal contribution to the adsorption of proteins. The supports obtained may be used for the immobilization and Chromatographic separation of biopolymers.Translated from Teoreticheskaya i Éksperimental'naya Khimiya, Vol. 23, No. 2, pp. 237–241, March–April, 1987.