Aminomethylation of formononetin and cladrin by primary amines |
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Authors: | S P Bondarenko M S Frasinyuk V P Khilya |
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Institution: | (1) Taras Shevchenko Kiev National University, 01033, Ukraine, Kiev, ul. Vladimirskaya, 64; |
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Abstract: | The reaction of natural isoflavones formononetin and cladrin with primary amines and formalin in the presence of a base catalyst
was studied. Several novel substituted 9,10-dihydro-4H,8H-chromeno 8,7-e]1,3]oxazin-4-ones containing alkyl, benzyl, or heterylalkyl substituents in the N-9 position were synthesized. |
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