Conversion of N-aromatic amides to O-aromatic esters |
| |
Authors: | Glatzhofer Daniel T Roy Raymond R Cossey Kimberly N |
| |
Affiliation: | Department of Chemistry and Biochemistry, The University of Oklahoma, Norman, Oklahoma 73019, USA. dtglatzhofer@chemdept.chem.ou.edu |
| |
Abstract: | [reaction: see text] N-Aromatic secondary amides can be transformed into O-aromatic esters in high yield via N-nitrosamide intermediates. The amides can be generated in situ from the corresponding aromatic amines or nitro compounds, and phenols can easily be made from the esters. The reaction can be modified by addition of methyl methacrylate or toluene at 0 degrees C to give polymerization or deamination, respectively. The rearrangement mechanism may involve radical formation and recombination. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|