| Purification and Characterization of an Antibacterial Peptide from Rana Temporaria Chensinensis Skin |
| |
| 作者姓名： | GOU Xiao jun LI Xiang hui DING Tian bing WANG Yong ting CHEN Huai yong HUANG Cheng fang DONG Qing chu and LI Qing shan * |
| |
| 作者单位： | GOU Xiao jun，LI Xiang hui，DING Tian bing，WANG Yong ting CHEN Huai yong，HUANG Cheng fang，DONG Qing chu and LI Qing shan * (College of Life Science，Jilin University，Changchun 130023，P.R. China |
| |
| 摘 要： | ＩｎｔｒｏｄｕｃｔｉｏｎＩｎａｄｄｉｔｉｏｎｔｏｔｈｅｈｉｇｈｌｙｓｐｅｃｉｆｉｃｃｅｌｌ－ｍｅｄｉａｔｅｄｉｍｍｕｎｅｓｙｓｔｅｍ，ｖｅｒｔｅｂｒａｔｅｓａｎｄｏｔｈｅｒｏｒｇａｎｉｓｍｓｈａｖｅａｄｅｆｅｎｓｅｓｙｓｔｅｍｍａｄｅｕｐｏｆｄｉｓｔｉｎｃｔｇｒｏｕｐｓｏｆｂｒｏａｄ－ｓｐｅｃｔｒｕｍａｎｔｉｂａｃｔｅｒｉａｌｐｅｐｔｉｄｅｓ［１—３］．Ａｎｔｉｂａｃｔｅｒｉａｌｐｅｐｔｉｄｅｓｃａｎｂｅｃｌａｓｓｉｆｉｅｄｉｎｔｏｔｗｏｇｒｏｕｐｓｂａｓｅｄｏｎｈａｖｉｎｇｄｉｓｕｌ－ｆｉｄｅ…
|
Purification and Characterization of an Antibacterial Peptide from Rana Temporaria Chensinensis Skin |
| |
| GOU Xiao jun,LI Xiang hui,DING Tian bing,WANG Yong ting CHEN Huai yong,HUANG Cheng fang,DONG Qing chu and LI Qing shan *.Purification and Characterization of an Antibacterial Peptide from Rana Temporaria Chensinensis Skin[J].Chemical Research in Chinese University,1999(4). |
| |
| Authors: | GOU Xiao jun LI Xiang hui DING Tian bing WANG Yong ting CHEN Huai yong HUANG Cheng fang DONG Qing chu and LI Qing shan |
| |
| Institution: | GOU Xiao jun,LI Xiang hui,DING Tian bing,WANG Yong ting CHEN Huai yong,HUANG Cheng fang,DONG Qing chu and LI Qing shan * |
| |
| Abstract: | The Rana temporaria chensinensis is an amphibian distributing mainly over the north of China. Its skin gland contains a variety of peptides, including antibacterial peptides. One of them, component 1, has been purified from the dried skin of R.temporaria chensinesis using a five step procedure. Purified component 1 has a molecular weight of 5 700 and its amino acid composition shows that it is devoid of disulfide bridges but rich in histine and glycine residues. Moreover, it has been found that it has a broad spectrum of antibacterial activity for Pseuctomonas aeruginosa, Escherichia coli, Bacillus sublilis, S. faccalis and Proteus vulgaris . |
| |
| Keywords: | Antibacterial activity Peptide Dried skin |
| 本文献已被 CNKI 等数据库收录！ |
