Conducting polymers in modelling transient potential of biological membranes |
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Authors: | Paczosa-Bator Beata Blaz Teresa Migdalski Jan Lewenstam Andrzej |
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Affiliation: | Faculty of Material Science and Ceramics, AGH-University of Science and Technology, Al. Mickiewicza 30, PL-30059 Cracow, Poland. |
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Abstract: | The possibility of using conducting polymer (CP) films doped with biological ligands as artificial biological membranes to study potential formation mechanisms is presented. Calcium and magnesium ion-binding anionic sites--asparagine, glutamine, adenosinotriphosphate and heparin are incorporated into the poly(pyrrole) film during electrochemical polymerization. This approach allows the competitive calcium-magnesium ion-exchange to be inspected by open circuit measurements. After a close-to-Nernstian sensitivity of the CP membranes was induced by soaking in alkaline solutions of calcium or magnesium, dynamic experiments were performed by a change in the bulk concentration of magnesium or calcium ions. A characteristic transitory potential response, though distinctively different for the calcium and magnesium ions, was observed and explained using the diffusion layer model (DML). |
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