基于原子磁力计的穿戴式脑磁图动态测量研究

脑磁图作为一种无创的脑功能成像技术，依靠超高的时间及空间溯源分辨率，在脑科学研究和临床应用领域中有着极其重要的价值．本文介绍了自主搭建的基于原子磁力计的穿戴式脑磁图系统，通过设计匀场补偿线圈组并结合参考传感器阵列，实现被试头部运动区域内剩磁在±1nT以内，保证动态测量过程中传感器输出维持在动态范围以内；同时提出了一种虚拟合成梯度去噪方法，显著抑制了环境共模噪声；最终在被试者头部自然运动状态下，成功检测到高信噪比的α节律信号与听觉诱发磁场信号，证实了该系统的有效性，为穿戴式脑磁图应用推广提供更多的可能性．

Moving Wearable Magnetoencephalography Measurement Study Based on Optically-pumped Magnetometer

Magnetoencephalography is a non-invasive technology for brain function imaging, which is of enormous value to brain science research and clinical application due to its ultra-high temporal and spatial trace resolution. In this paper, we introduce a self-built and atomic magnetometer based wearable magnetoencephalography system. By designing bi-planar coils system and combining with reference sensor array, the residual magnetic field in the subject's head movement area is controlled to be within ±1 nT, which ensures the sensors are maintained within their dynamic range during the moving measurement. At the same time, a virtual gradiometer-based noise reduction method is proposed to suppress the common-mode magnetic-field noise. Finally, the alpha rhythm and auditory evoked magnetic field signals with high signal-to-noise ratio are successfully detected under the subject's natural head movement and the effectiveness of the system is confirmed. This study could provide more possibilities for the application and promotion of moving wearable magnetoencephalography.