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Cyclisation des amides d'acides phénylthio-1 glyoxaliques avec les dérives carbonylés |
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| Authors: | Pierre Girault Jacques Perronnet |
| Abstract: | The carbonyl-containing compounds react with the amides of phenyl-1-thioglyoxalic acids ( 3 ), and if methyl iodide is present, cause cyclisation into 4-methylthio-5-phenyl-2,5-dihydrooxazol-5-ols ( 4 ). The ketal hydroxyl group of the latter can be methylated. When a hydrogen atom exists in the 2-position (cyclisation with an aldehyde), its elimination provides an oxazole 7 . |
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