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Thermal Behaviour of Pharmacologically Active Lithium Compounds
Authors:Tobón-Zapata  G E  Ferrer  E G  Etcheverry  S B  Baran  E J
Institution:(1) Centro de Química Inorgánica (CEQUINOR), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, C. Correo 962, 1900 La Plata, Argentina
Abstract:The thermal decompositions of a series of simple lithium compounds (carbonate, sulfate, acetate, citrates, aspartates and glutamates) currently used in the treatment of manic-depressive psychosis and related disorders were investigated by means of TG and DTA measurements in oxygen atmosphere. Pyrolysis residues were characterized by infrared spectroscopy. The stabilities of the hydrates and intermediate phases generated during the degradation processes are discussed. This revised version was published online in July 2006 with corrections to the Cover Date.
Keywords:lithium drugs  thermal decomposition  thermal stability
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