Synthesis and modification of 4-hydroxy-2-methyl-3-(2-chloro-2-propenyl)quinoline |
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| Authors: | A A Avetisyan I L Aleksanyan A A Pivazyan |
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| Institution: | (1) Yerevan State University, Yerevan, 375025, Armenia |
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| Abstract: | 4-Hydroxy-2-methyl-3-(2-chloro-2-propenyl)quinoline was prepared by O-allylation of 4-hydroxy-2-methylquinoline followed by the Claisen rearrangement of the 2-methyl-4-(2-chloro-2-propenyloxy)quinoline obtained. Chemical modifications of 4-hydroxy-2-methyl-3-(2-chloro-2-propenyl)quinoline resulted in the synthesis of 4-amino-2-methyl-3-(2-methyl-3-indolyl)quinoline. |
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