A new phenanthrene glycoside and other constituents from Dioscorea opposita |
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Authors: | Sautour Marc Mitaine-Offer Anne-Claire Miyamoto Tomofumi Wagner Hildebert Lacaille-Dubois Marie-Aleth |
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Institution: | Laboratoire de Pharmacognosie, Unité UMIB, EA 3660, Faculté de Pharmacie, Université de Bourgogne, Dijon, France. |
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Abstract: | Phytochemical investigation of the rhizome of Dioscorea opposita has led to the isolation of a new phenanthrene glycoside, 3,4,6-trihydroxyphenanthrene-3-O-beta-D-glucopyranoside (1), and five known compounds, soyacerebroside I (2), adenosine (3), beta-sitosterol (4), palmitic acid (5) and palmitoyloleoylphosphatidylcholine (6). Their structures were determined by spectroscopic methods, including 1D- and 2D-NMR. Compounds 1-6 exhibited no antifungal activity against the human pathogenic yeasts Candida albicans, C. glabrata and C. tropicalis. |
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