Phytochemical constituents of the pericarps of Illicium difengpi and their anti-inflammatory activity |
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| Authors: | De-Sheng Ning Yu-Xia Fu Li-Yan Peng Hui Tang Lian-Chun Li Xing-De Wu |
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| Institution: | 1. Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin, PR China;2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming, PR China |
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| Abstract: | AbstractPhytochemical investigation on the pericarps of Illicium difengpi lead to the isolation and structure elucidation of a new sesquiterpene, sesquicaranoic acid C (1), a new neolignan, difengpiol C (2), and 10 known compounds. The structures and absolute configurations of two new compounds were determined by a combination of NMR and CD spectroscopic analyses. All isolates were evaluated for their inhibitory effects on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 cells. |
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| Keywords: | Illicium difengpi sesquiterpene neolignan anti-inflammatory |
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