A new epicatechin glucopyranoside derivative from Styrax suberifolius |
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| Authors: | Bing-Lei Liu Xin Hu Hua-Liang He Lin Qiu You-Zhi Li |
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| Institution: | 1. Hunan Provincial Engineering &2. Technology, Research Center for Biopesticide and Formulation Processing, Hunan Agricultural University, Changsha, China;3. Hunnan Cotton Science Institute, Changde, China;4. National Research Center of Engineering &5. Technology for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha, China |
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| Abstract: | AbstractA new derivative of epicatechin glucopyranoside, (2R,3R)-3,7,4'-trihydroxy-5,3'-dimethoxyflavan 7-O-β-d-glucopyranoside (1), together with three mononuclear phenolic acid esters, methyl orsellinate (2), ethyl orsellinate (3) and methyl β-orcinolcarboxylate (4) were isolated from the bark of Styrax suberifolius. The structures of 1–4 were determined on the basis of extensive analysis of NMR and MS spectra combined with chemical hydrolysis. The antifungal activities of the isolated compounds against three plant pathogenic fungi, Alternaria solani, Fusarium oxysporum and Phomopsis cytospore were evaluated using radial growth inhibition assay. Compounds 2, 3 and 4 exerted selective inhibitory activities against the tested fungi. Among of them, methyl β-orcinolcarboxylate (4) exhibited obvious inhibitory effect against P. cytospore, with an inhibition rate of 86.72% at 100?μg/ml. |
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| Keywords: | Styrax suberifolius epicatechin derivative flavonoid glycoside antifungal activity |
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