A highly sensitive and fast responsive fluorescent probe for SO2 derivatives and its application in living cell imaging |
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| Authors: | Mengsheng Xu Man Li Zhiwei Ma Di Zhang |
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| Affiliation: | 1. College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai, China;2. Henan Cereal Quality and Safety Testing Key Laboratory, Institute of Quality Standards and Testing Technology for Agro-Products, Henan Academy of Agricultural Sciences, Zhengzhou, China;3. Henan Cereal Quality and Safety Testing Key Laboratory, Institute of Quality Standards and Testing Technology for Agro-Products, Henan Academy of Agricultural Sciences, Zhengzhou, China;4. Faculty of Science, Henan University of Animal Husbandry and Economy, Zhengzhou, China |
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| Abstract: | AbstractA new fluorescence probe 1 for sulfur dioxide derivatives has been developed which acts through nucleophilic addition of the derivatives and shows high stability, specificity, and sensitivity. In the presence of SO2 derivatives, the fluorescence intensity of probe 1 significantly decreases within a short time period of 40?s, along with a low detection limit of 0.32?µM. Fluorescence imaging capability of probe 1 was also investigated, showing clear detection of SO2 derivatives in living cells. The results indicate that this probe has a great potential for the detection of SO2 derivatives in broad biological and relevant samples. |
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| Keywords: | SO2 fluorescent probe nucleophilic addition biological imaging |
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