One new sterpurane sesquiterpene from cultures of the basidiomycete Pholiota nameko |
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| Authors: | Wan-Rong Niu Cong-Liang Guo Deng-Ji Lou Rui-Ting Li Qiao Xiang Yu-Lin Zou |
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| Affiliation: | 1. Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming , P. R. China;2. Yunnan Institute of Materia Medica, Kunming , P. R. China;3. College of Resources and Enviroment, Yuxi Normal University, Xuyi , P. R. China |
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| Abstract: | AbstractOne new sterpurane sesquiterpene (1), named (3R,6S,7S,8R,10S)-3,7,14-trihydroxy-1-sterpurene was isolated from cultures of the basidiomycete Pholiota nameko. The structure of new compound was elucidated by extensive spectroscopic. Additionally, a single crystal X-ray diffraction not only confirmed the structure, but also determined the absolute configuration of the new compound. The compound was evaluated for cytotoxicity against five human cancer cell lines, but no significant cytotoxicity were found (IC50 values > 40?μM). |
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| Keywords: | basidiomycete Pholiota nameko sesquiterpene X-ray cytotoxicity |
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