Phytochemical study,potential cytotoxic and antioxidant activities of selected food byproducts (Pomegranate peel,Rice bran,Rice straw & Mulberry bark) |
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| Authors: | Khaled M Meselhy Manal M Shams Noheir H Sherif Sawsan M El-sonbaty |
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| Institution: | 1. Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, Egypt;2. kmeselhy@hotmail.com;4. Department of Medicinal Plants and Natural Products, National Organization for Drug Control &5. Research (NODCAR), Giza, Egypt;6. Drug Radiation Research Department, National Centre for Radiation Research and Technology (NCRRT), Atomic Energy Authority, Nasr City, Egypt;7. Department of Pharmacognosy, Faculty of Pharmacy, Nahda University, Beni Suef, Egypt |
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| Abstract: | AbstractThe aim of the study is to evaluate common food by-products (Pomegranate peel, Rice bran, Rice straw & Mulberry bark) to screen out their medicinal importance such as cytotoxic & antioxidant activities. HPLC revealed that all tested samples were rich in phenolics. Tested samples exerted significant antioxidant activity with high potency to Pomegranate peel. All tested extracts were able to reduce cell viability of tested cell lines in a dose-response manner after treatment. In most cases, the IC50 values were under 30 μg/ml except IC50 of pomegranate peel against breast cell line (42.4?ug/ml). The antioxidant and cytotoxic properties of pomegranate peel, rice bran, rice straw and mulberry bark have been attributed to synergetic effects of phenolic phytochemicals. |
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| Keywords: | Pomegranate rice bran rice straw mulberry HPLC antioxidant and cytotoxic |
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