Two new compounds from the heartwood of Dalbergia melanoxylon |
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Authors: | Shuai Lin Rong-Hua Liu Guang-Qiang Ma Dan-Yi Mei Lan-Ying Chen |
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Institution: | 1. Key Laboratory of Innovation Drug and Efficient Energy-saving Pharmaceutical Equipment, Jiangxi University of Traditional Chinese Medicine
, Nanchang , China;2. College of Basic Medical, Jiangxi University of Traditional Chinese Medicine
, Nanchang , China |
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Abstract: | AbstractA new neoflavonoid, named S(+)-3′-hydroxy-4′,2,4,5-tetramethoxydalbergiquinol (1), and a new benzofuran, named (2S,3S)-5-hydroxy-6-methoxy-3-methyl-2-(4′-hydroxyphenyl)-2,3dihydrobenzofuran (4), together with two known neoflavonoids, were isolated from the heartwood of Dalbergia melanoxylon. Their structures were elucidated by a combination of spectroscopic methods and comparison with the literature. Compounds 1–4 were evaluated for inhibitory activity against Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 6538, Salmonella enteri CMCC 50041 and Candida albicans ATCC 289065, which all exhibited inactive or weak activity. |
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Keywords: | Neoflavonoid benzofuran Dalbergia melanoxylon antimicrobial activity |
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