Simple isophthalamides/dipicolineamides as active transmembrane anion transporters |
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Authors: | Giacomo Picci Israel Carreira-Barral Daniel Alonso-Carrillo David Sanz-González Pablo Fernández-López María García-Valverde |
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Institution: | 1. Dipartimento di Scienze Chimiche e Geologiche, Università degli Studi di Cagliari, Monserrato, Italy;2. Departamento de Química, Universidad de Burgos, Burgos, Spain |
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Abstract: | ABSTRACTEight N,N´-diarylisophthalamide/dipicolineamide derivatives have been synthesised and fully characterised, both in solution and in the solid state. The transmembrane anion transport properties of these compounds have been studied by chloride-selective electrode and fluorescence experiments. The substitution pattern of the aromatic moieties determines the transport properties of these systems, with those containing electron-withdrawing groups in their structures being the most active ones of the series. |
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Keywords: | Anion binding anion transport ion-selective electrode liposomes |
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