A new antimicrobial sesquiterpene isolated from endophytic fungus Cytospora sp. from the Chinese mangrove plant Ceriops tagal |
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| Authors: | Qin Deng Gang Li Mengyu Sun Jing Xu |
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| Institution: | 1. Key Laboratory of Tropical Biological Resources of Ministry of Education, Institute of Tropical Agriculture and Forestry, Hainan University, Haikou, P. R. China;2. Key Laboratory of Advanced Materials of Tropical Island Resources of Ministry of Education, College of Material and Chemical Engineering, Hainan University, Haikou, P. R. China;3. Key Laboratory of Advanced Materials of Tropical Island Resources of Ministry of Education, College of Material and Chemical Engineering, Hainan University, Haikou, P. R. China |
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| Abstract: | AbstractChemical examination of Chinese mangrove Ceriops tagal endophytic Cytospora sp., yielded a new biscyclic sesquiterpene seiricardine D (1), and eight known metabolites, xylariterpenoid A (2a), xylariterpenoid B (2b) and regiolone (3) 4-hydroxyphenethyl alcohol (4), (22E, 24R)5, 8-epidioxy-5α, 8α-ergosta-6,22E-dien-3ß-ol (5), (22E, 24R)5, 8-epidioxy-5α, 8α-ergosta-6,9(11), 22-trien-3 ß-ol (6), ß-sitosterol (7) and stigmast-4-en-3-one (8). These structures were unambiguously elucidated on the basis of extensive NMR spectroscopic and mass spectrometric analyses. The antimicrobial activities of compounds 1–8 and their effects on a panel of plant and human pathogens were evaluated. |
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| Keywords: | Ceriops tagal Cytospora sp seiricardine D antimicrobial activity |
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