Reaction of barbituric/thiobarbituric acid with phosphines or phosphites and dialkyl acetylenedicarboxylates for synthesis of phosphorus zwitterions or phosphonate derivatives |
| |
| Authors: | Mohammad Anary-Abbasinejad Fereshteh Nejad-Shahrokhabadi |
| |
| Institution: | 1. Department of Chemistry, Faculty of Science, Vali-e-Asr University of Rafsanjan, Rafsanjan, Iranm.anary@vru.ac.ir;3. Department of Chemistry, Faculty of Science, Vali-e-Asr University of Rafsanjan, Rafsanjan, Iran |
| |
| Abstract: | AbstractA three-component reaction between barbituric/thiobarbituric acid, phosphines, and dialkyl acetylenedicarboxylates in dry acetonitrile led to the formation of barbiturate/thiobarbiturate-functionalized stable zwitterionic salts in a one-pot process. When trialkyl phosphites were used instead of phosphines, barbiturate/thiobarbiturate-functionalized phosphonates were obtained in good yields. |
| |
| Keywords: | Phosphine phosphite zwitterionic salt barbituric acid thiobarbituric acid |
|
|
