Microwave-assisted and catalyst-free sulfenylation of imidazo[2,1-b]thiazoles with sulfonyl hydrazides in water |
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| Authors: | Shaohua Wang Run Luo Lina Guo Tianxi Zhu Xu Chen Wenjie Liu |
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| Institution: | 1. School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Guangzhou, P.R. of China;2. Guangdong Cosmetics Engineering &3. Technology Research Center, Guangzhou, P.R. of Chinawangshaohua108@163.com wjliu1113@126.com;5. Technology Research Center, Guangzhou, P.R. of China |
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| Abstract: | AbstractAn efficient microwave-assisted and catalyst-free sulfenylation of imidazo2,1-b]thiazoles with sulfonyl hydrazides has been developed in water. This method is practical and environmental friendly, and can be performed within a short reaction time. The sulfenylation reaction shows high regioselectivity, and excellent functional-group compatibility, giving the desired products in moderate to good yields. |
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| Keywords: | Sulfenylation imidazo[21-b]thiazole sulfonyl hydrazide catalyst-free regioselectivity |
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