A chemo- and regio-selective three-component dihydropyrimidinone synthesis |
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| Authors: | Bailey Chris D Houlden Chris E Bar Grégory L J Lloyd-Jones Guy C Booker-Milburn Kevin I |
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| Institution: | School of Chemistry, University of Bristol, Cantock's Close, Bristol, UK BS8 1TS. |
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| Abstract: | A selective three-component coupling, involving co-condensation of aldehyde pairs with substituted ureas under Lewis acid catalysis, provides rapid access to highly functionalised dihydropyrimidinones; sulfamides react analogously. |
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