|
|||||
|
|
| Preparation and Crystal Structure of 3-（2-Hydroxyphenyl） -6- （4-nitrophenyl）-7H- 1,2,4-triazolo[3,4-b][1, 3,4]thiadiazine | |
| 引用本文： | ZOU Kai-huang 1,2,ZHANG Li-xue 1**,ZHANG An-jiang1 LEI Xin-xiang1,HUANG Hui-hua1 and ZHANG Zi-yi3 1. School of Chemistry and Materials Science,Wenzhou Normal College,Wenzhou 325027,P. R. China, 2. Department of Biology and Chemistry,Fujian Educational College,Fuzhou 350001,P. R. China, 3. College of Chemistry and Chemical Engineering,Lanzhou University,Lanzhou 730000,P. R. China. Preparation and Crystal Structure of 3-（2-Hydroxyphenyl） -6- （4-nitrophenyl）-7H- 1,2,4-triazolo[3,4-b][1, 3,4]thiadiazine[J]. 高等学校化学研究, 2005, 21(1): 69-72 |
| 作者姓名： | ZOU Kai-huang 1 2 ZHANG Li-xue 1** ZHANG An-jiang1 LEI Xin-xiang1 HUANG Hui-hua1 and ZHANG Zi-yi3 1. School of Chemistry and Materials Science Wenzhou Normal College Wenzhou 325027 P. R. China 2. Department of Biology and Chemistry Fujian Educational College Fuzhou 350001 P. R. China 3. College of Chemistry and Chemical Engineering Lanzhou University Lanzhou 730000 P. R. China |
| 作者单位： | ZOU Kai-huang 1，2，ZHANG Li-xue 1**，ZHANG An-jiang1 LEI Xin-xiang1，HUANG Hui-hua1 and ZHANG Zi-yi3 1. School of Chemistry and Materials Science，Wenzhou Normal College，Wenzhou 325027，P. R. China; 2. Department of Biology and Chemistry，Fujian Educational College，Fuzhou 350001，P. R. China; 3. College of Chemistry and Chemical Engineering，Lanzhou University，Lanzhou 730000，P. R. China |
| 摘 要： | Introduction3,6- Disubstituted- 7H- 1 ,2 ,4- triazolo[3,4- b][1 ,3,4]thiadiazines are amongst the various hete-rocycles that received considerable attention duringthe last two decades as potential biologically activeagents.This kind of N- bridged heterocycles hasbeen reported to possess the wide spectrum of bio-logical properties,such as antimicrobial[1] ,an-tibacterial,antifungal[2 ] ,antiinflammatory[3 ] ,di-uretic[4] ,anthelmintic,and analgesic properties[5] .They can be also used as plant… |
| 关 键 词： | π-π stacking interaction |
| 收稿时间： | 2004-02-05 |
Preparation and Crystal Structure of 3-(2-Hydroxyphenyl)-6-(4-nitrophenyl)-7H-1,2,4-triazolo[3,4-b][1,3,4 ]thiadiazine |
|
| ZOU Kai-huang,ZHANG Li-xue,ZHANG An-jiang,LEI Xin-xiang,HUANG Hui-hua,ZHANG Zi-yi. Preparation and Crystal Structure of 3-(2-Hydroxyphenyl)-6-(4-nitrophenyl)-7H-1,2,4-triazolo[3,4-b][1,3,4 ]thiadiazine[J]. Chemical Research in Chinese University, 2005, 21(1): 69-72 | |
| Authors: | ZOU Kai-huang ZHANG Li-xue ZHANG An-jiang LEI Xin-xiang HUANG Hui-hua ZHANG Zi-yi |
| Affiliation: | 1. School of Chemistry and Materials Science, Wenzhou Normal College, Wenzhou 325027, P. R. China; 2. Department of Biology and Chemistry , Fujian Educational College, Fuzhou 350001, P. R. China; 3. College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China |
| Abstract: | 3-(2-Hydroxyphenyl)-6-(4-nitrophenyl)-7H-1,2,4-triazolo[3,4-b][1,3,4] thiadiazine, C16H11N5O3S, was prepared by the cyclization of 3-(2-hydroxyphenyl)-4-amino-5-mercapto-1,2,4-triazole with 2-bromo-4-nitroacetophenone. The compound was characterized by means of elemental analysis, IR, 1H NMR, 13C NMR, mass spectrometry, and X-ray diffraction. The compound crystallizes in a monoclinic system with space group Cc, a=2.1853(4) nm, b=2.1192(5) nm, c=1.3526(3) nm, β=95.21(2)°, V=6.238(2) nm3 , Dcalcd.=1.505 Mg/m3, Z=16, F(000)=2916, R1=0.0501, wR2=0.0427. A comparison between the crystal structures of 1,2,4-triazolo[3,4-b] [1,3,4] thiadiazine and 1,2,4-triazolo[3,4-b][1,3,4] thiadiazole was made in the structural view. A two-dimensional network is formed by hydrogen bonds and π-π stacking interactions. |
| Keywords: | Triazolothiadiazine Preparation Spectral characterization Crystal structure |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |
| 点击此处可从《高等学校化学研究》浏览原始摘要信息 | |
| 点击此处可从《高等学校化学研究》下载全文 | |