| 香鱼嗜水气单胞菌染病后主要靶器官组织病理学观察 |
| |
| 引用本文： | 李明云,张呈念,苗亮,王成义,陈炯,史雨红.香鱼嗜水气单胞菌染病后主要靶器官组织病理学观察[J].宁波大学学报(理工版),2011,24(3):1-4. |
| |
| 作者姓名： | 李明云 张呈念 苗亮 王成义 陈炯 史雨红 |
| |
| 作者单位： | 1. 宁波大学 应用海洋生物技术教育部重点实验室,浙江宁波,315211
2. 宁波大学 应用海洋生物技术教育部重点实验室,浙江宁波315211;温州科技职业学院,浙江温州325006 |
| |
| 基金项目： | 973计划前期研究专项(2008CB117015); 长江学者和创新团队发展计划(IRT0734) |
| |
| 摘 要： | 从患病香鱼的体腔液中分离获得嗜水气单胞菌病原,用培养稀释的菌液,经腹腔注射人工感染健康香鱼,出现典型出血症后,进行相关的组织病理变化的观察.组织病理显示：脾、肝、肠是细菌侵染重要的靶器官;且脾、肝、肠的变化主要表现为广泛的组织细胞变性、坏死,大量单核细胞、浆细胞等免疫细胞增生.病理超微切片观察显示：在患病香鱼脾脏组织中发现大量长2μm、宽0.5μm左右的细菌,脾脏细胞损伤主要表现为线粒体嵴消失、溶酶体增多,细胞间隙增大,细胞内出现空泡;肝脏主要表现为脂肪变性,溶酶体增多,线粒体嵴断裂、肝糖原颗粒减少;患病香鱼肠道细胞间隙变大,核蛋白体大量或全部脱落,线粒体膜破损,嵴断裂成髓样病变,形成髓样小体.
|
| 关 键 词： | 嗜水气单胞菌 香鱼 组织病理 |
Histopathological Changes in Main Target Organs of AYU(Plecoglossus altivelis) Infected with Aeromonas hydrophila |
| |
| LI Ming-yun,ZHANG Cheng-nian,MIAO Liang,WANG Cheng-yi,CHEN Jiong,SHI Yu-hong.Histopathological Changes in Main Target Organs of AYU(Plecoglossus altivelis) Infected with Aeromonas hydrophila[J].Journal of Ningbo University(Natural Science and Engineering Edition),2011,24(3):1-4. |
| |
| Authors: | LI Ming-yun ZHANG Cheng-nian MIAO Liang WANG Cheng-yi CHEN Jiong SHI Yu-hong |
| |
| Institution: | LI Ming-yun 1,ZHANG Cheng-nian 1,2,MIAO Liang 1,WANG Cheng-yi 1,CHEN Jiong 1,SHI Yu-hong 1(1.Key Laboratory ofApplied Marine Biotechnology,Ministry of Education,Ningbo University,Ningbo 315211,China,2.Wenzhou Vocational College of Science & Technology,Wenzhou 325006,China) |
| |
| Abstract: | In this paper studies are conducted on the pathological changes of blood and related organizations of Plecoglossus altivelis artificially injected with Aeromonas hydrophila,which was first separated from the coelomic fluidthe of the sicken Plecoglossus altivelis and then diluted followed by being cultivated.Pathological changes of Pleccoglossus altivelis tissues(gill,liver,spleen,kidney,heart & intestine) were observed,finding that the liver,spleen,intestine are the major organelles which are easily infecte... |
| |
| Keywords: | Aeromonas hydrophila Pleccoglossus altivelis histopathology |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
