Thermodynamics and the mechanism of interaction of uracil with amino acids in water

Interaction of most of the side groups of amino acids with uracil and their dehydration do not contribute significantly to the pair interaction coefficients. It has been suggested that the interaction between the terminal groups of amino acids and the side groups of uracil (NH, CO) occurs by the acid-base mechanism. The possibility was found of formation of uracil+l-proline associates, owing to favorable configurations of the components, uracil+l-tryptophan associates, owing to π-π electronic interaction between their aromatic rings, and uracil+l-lysine: HCl, owing to the side ammonium group in amino acid. Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 932–934, May, 1997.