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Studyon Fluorescence Property of SparfloxacinDerivatizing System and its Application
引用本文:Li Ming DU, Jing ZHOU. Qing Qin XU,Zhe Feng FAN, Rong YUAN (Center of Analysis and Test,Shanxi Normal University,Linfen 041004). Studyon Fluorescence Property of SparfloxacinDerivatizing System and its Application[J]. 中国化学快报, 2000, 11(3): 255-258
作者姓名:Li Ming DU   Jing ZHOU. Qing Qin XU  Zhe Feng FAN   Rong YUAN (Center of Analysis and Test  Shanxi Normal University  Linfen 041004)
作者单位:Center of Analysis and Test,Shanxi Normal University,Linfen 041004
摘    要:Spartloxacin (SPFX) is the fourth generation of the antibacterial quinolones. Due to itsintensive and efficient antibacterial activity compared to the common quinolones '. it hasbeen widely used in clinical practice. Nevertheless. because of the structural dit'ferencesbetween SPFX and other quinolones. the fluorescence of SPFX is so weak that it can notbe determined by means of fluorescence spectra. Hence, it will be of great interest tomake a detailed study on its fluorescence enhancemen…


Study on Fluorescence Property of Sparfloxacin Derivatizing System and its Application
Li Ming DU,Jing ZHOU,Qing Qin XU,Zhe Feng FAN,Rong YUAN. Study on Fluorescence Property of Sparfloxacin Derivatizing System and its Application[J]. Chinese Chemical Letters, 2000, 11(3): 255-258
Authors:Li Ming DU  Jing ZHOU  Qing Qin XU  Zhe Feng FAN  Rong YUAN
Abstract:In acid medium, sparfloxacin is oxidized by nitrous acid. then reacts with hydrobromic acid to form a new fluorescence substance. which can emit the strong fluorescence. which is 151 fold more than that of sparfloxacin itself. By this . a new sensitive method for the determination of sparfloxacin in human urine by derivative-synchronous fluorescence is presented with good results.
Keywords:Sparfloxacin   nitrous acid  derivative-synchronous fluorescence   human urine.
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