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Energising the E-factor: The E+-factor
Authors:Florian Tieves  Fabio Tonin  Elena Fernández-Fueyo  John M. Robbins  Bettina Bommarius  Andreas S. Bommarius  Miguel Alcalde  Frank Hollmann
Affiliation:1. Department of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629, HZ, Delft, the Netherlands;2. School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, 950 Atlantic Drive, Atlanta, GA, 30332, USA;3. Department of Biocatalysis, Institute of Catalysis, CSIC, 28049, Madrid, Spain;4. School of Chemistry and Biochemistry, Georgia Institute of Technology, 901 Atlantic Drive, N.W., Atlanta, GA 30332, USA
Abstract:The E-factor has become an important measure for the environmental impact of (bio)chemical reactions. However, summing up the obvious wastes generated in the laboratory neglects energy-related wastes (mostly greenhouse gases) which are generated elsewhere. To estimate these wastes, we propose to extend the E-factor by an energy-term (E+-factor). At the example of a lab-scale enzyme fermentation, we demonstrate that the E+-factor can constitute a multiple of the classical E-factor and therefore must not be neglected striving for a holistic estimation of the environmental impact.
Keywords:E-factor  Green chemistry  Peroxygenases  Oxyfunctionalisation chemistry  Biocatalysis
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