Palladium(II) complexes of Schiff bases derived from 5-amino-2,4-(1H, 3H)pyrimidinedione (5-aminouracil) and 1,2-dihydro-1,5-dimethyl-2-phenyl-4-amino-3H-pyrazol-3-one

Summary New palladium(II) complexes of Schiff bases, obtained from 5-aminouracil, (AUH), and acetylacetone (AUAcAcH₂), benzaldehyde (AUBALH), furan-2-aldehyde (AUFALH), 2-hydroxynaphthaldehyde (AUNALH₂), pyridine-2-aldehyde (AUPyALH) or salicylaldehyde (AUSALH₂) and from 1,2-dihydro-1,5-dimethyl-2-phenyl-4-amino-3H-pyrazol-3-one (AAPy) and acetylacetone (AAPyAcAcH), 2-hydroxyacetophenone (AAPyAPH), furan-2-aldehyde (AAPyFAL), pytidine-2-aldehyde (AAPyPyAL), or salicylaldehyde (AAPySALH), have been prepared. The complexes, with formulae PdL₂Cl₂ (L=AUBALH, AUFALH or AUSALH₂); PdLCl₂ (L=AUAcAcH₂, AUNALH₂, AUPyALH, AAPyFAL or AAPyPyAL) and PdLCl (L=AAPyAcAc or AAPySAL) were characterized by elemental analysis, i.r. and electronic spectral studies, thermogravimetric analyses and magnetic and conductance measurements. The x-ray powder diffraction pattern of one of the complexes was also examined. The complexes were screened for their possible antitumour activityin vitro.