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| 基质分散固相萃取-液相色谱-离子阱质谱法检测罐头食品中双酚类化合物残留 | |
| 引用本文： | 梁凯,邓晓军,伊雄海,赵晓亚,郭德华,赵善贞,陈舜胜,王鹏,朱坚.基质分散固相萃取-液相色谱-离子阱质谱法检测罐头食品中双酚类化合物残留[J].分析化学,2012,40(5):705-712. |
| 作者姓名： | 梁凯 邓晓军 伊雄海 赵晓亚 郭德华 赵善贞 陈舜胜 王鹏 朱坚 |
| 作者单位： | 1. 上海海洋大学,上海,200433 2. 上海出入境检验检疫局,上海,200135 3. 湖北出入境检验检疫局,武汉,430022 |
| 基金项目： | 上海市科研基地能力提升项目，质检公益性行业专项，国家质检总局课题，上海检验检疫局科技专项 |
| 摘 要： | 建立了采用基质分散固相萃取-液相色谱四级杆串联线性离子阱质谱分析罐头食品中双酚类化合物残留的方法.样品中的双酚类化合物残留经0.1％甲酸乙腈提取,基质分散固相萃取净化,外标法定量,液相色谱-质谱测定.使用数据相关采集扫描功能(IDA)结合增强离子产物(EPI)模式对样品中的双酚类进行定性分析,并建立双酚类的二级子离子谱库.通过MRM模式对双酚类进行定量分析,双酚类化合物在4种罐头食品中的平均回收率为49.3％～128.4％(n=6)；相对标准偏差在3.2％～14.4％(n-6)之间,可以满足对罐头食品中的双酚类残留的快速同时定性与定量检测的要求. |
| 关 键 词： | 双酚类化合物 基质分散固相萃取 四极杆串联线性离子阱质谱 QuEChERS 罐头食品 |
Simultaneous Determination of Bisphenol Compounds in Canned Food by Matrix Solid-Phase Dispersion and Liquid Chromatography-Tandem Quadrupole Linear Ion Trap Mass Spectrometry |
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| LIANG Kai , DENG Xiao-Jun , YI Xiong-Hai , ZHAO Xiao-Ya , GUO De-Hua , ZHAO Shan-Zhen , CHEN Shun-Sheng , WANG Peng , ZHU Jian.Simultaneous Determination of Bisphenol Compounds in Canned Food by Matrix Solid-Phase Dispersion and Liquid Chromatography-Tandem Quadrupole Linear Ion Trap Mass Spectrometry[J].Chinese Journal of Analytical Chemistry,2012,40(5):705-712. | |
| Authors: | LIANG Kai DENG Xiao-Jun YI Xiong-Hai ZHAO Xiao-Ya GUO De-Hua ZHAO Shan-Zhen CHEN Shun-Sheng WANG Peng ZHU Jian |
| Institution: | 1(Shanghai Ocean University,Shanghai 200433,China) 2(Shanghai Entry-Exit Inspection and Quarantine Bureau,Shanghai 200135,China) 3(Hubei Entry-Exit Inspection and Quarantine Bureau,Wuhan 430022,China) |
| Abstract: | A method based on matrix solid-phase dispersion and liquid chromatography-quadrupole/linear ion trap-mass spectrometry(MSPD-LC/QqLIT) for qualitative and quantitative determination of bisphenol compounds in canned food was presented.Bisphenol residues were extracted with acetonitrile solution containing 0.1% formic acid,followed by a further clean-up procedure using QuEChERS method.Bisphenol compounds were separated upon a C18 column and detected by liquid chromatographic-tandem mass spectrometry.Information dependent acquisition scan function(IDA) combined with enhanced product ion scan(EPI) library was used to confirm the bisphenol compounds,while quantification analysis was operated by MRM mode using external standard method simulta-neously.The recoveries ranged from 49.3%-128.4%(n=6) with RSD from 3.2% to 14.4%(n=6) in 4 kinds of canned food matrices respectively.The method is proved to be quick and effective for simultaneosly qualitative and quatitative determination of bisphenol residues in canned foodstuffs. |
| Keywords: | Bisphenol compounds Matrix solid-phase dispersion Tandem quadrupole-linear ion trap-mass spectrometry QuEChERS Canned food |
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