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Carbolines. 14. Synthesis of 5-azaellipticine
Authors:V. V. Kononova  A. A. Semenov
Affiliation:(1) Irkutsk Institute of Organic Chemistry, Siberian Branch, Academy of Sciences of the USSR, 664033 Irkutsk
Abstract:3-Acetyl-4-methylaminopyridine was obtained by cyanation of 3-acetylpyridine ethyleneketal N-oxide and subsequent chemical transformations of the nitrile group. Condensation of this product with oxindole led to the synthesis of 5H-5,11-dimethylindolo [3,2-j]-1,4-naphthyridine — the aza analog of the alkaloid ellipticine.See [1] for communication 13.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1211–1214, September, 1982.
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