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1-(Ethoxymethyl)-6-(phenylselenyl)-5-ethyl uracil: a nucleoside analog
Authors:G Mazumder  M De  A Mukhopadhyay  AK Das  SK Mazumder  V Bertolasi  RF Schinazi
Institution:(1) Department of Materials Science, Indian Association for the Cultivation of Science, Jadavpur, Calcutta, 700032, India;(2) Department of Physics, Jadavpur University, Jadavpur, Calcutta, 700032, India;(3) Department of Biotechnology, Indian Institute of Technology, Kharagpur, 721302, India;(4) Department of Chemistry, University of Ferrara, I-44100 Ferrara, Italy;(5) Veterans Administration Medical Centre (Atlanta), Emory, University School of Medicine, Atlanta, Georgia, 30303
Abstract:The compound, 1-(ethoxymethyl)-6-(phenylselenyl)-5-ethyl uracil, crystallizes in the monoclinic space group P21/n with unit cell parameters a = 5.304(1), b = 21.261(4), c = 13.996(4) Å, beta = 94.30(2)°, and Z = 4. The acyclic chain C1prime, O4prime, C4prime, C5prime is in fully extended form and nearly perpendicular to the uracil base. The molecules are held together by van der Waal's forces.
Keywords:acyclonucleoside analog  6-(phenyl selenyl) uracil derivative  crystal structure
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