Rhodium-catalyzed tandem conjugate addition-Mannich cyclization reaction: straightforward access to fully substituted tetrahydroquinolines |
| |
Authors: | Youn So Won Song Ju-Hyun Jung Dai-Il |
| |
Institution: | Department of Chemistry, Pukyong National University, Nam-Gu, Busan 608-737, Korea. sowony@pknu.ac.kr |
| |
Abstract: | A new Rh(I)-catalyzed tandem conjugate addition-Mannich cyclization reaction of imine-substituted electron-deficient alkenes with arylboronic acids has been developed to afford 2,3,4-trisubstituted 1,2,3,4-tetrahydroquinolines. This is the first example involving imine group as a secondary electrophile in Rh(I)-catalyzed tandem reactions. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|