|
|||||
|
|
Effect of cyclodextrins on the viability of endothelial cells |
|
| Authors: | D. Castagne L. Belhadj Salem L. Delattre B. Nusgens G. Piel |
| Affiliation: | 1. Laboratory of Pharmaceutical Technology, Department of Pharmacy, University of Liège, 1 av. de l’H?pital, 4000, Liège, Belgium 2. Laboratory of Connective Tissues Biology, University of Liège, 3 av. de l’H?pital, 4000, Liège, Belgium |
| Abstract: | Natural cyclodextrins (CD) and some of their derivatives have been tested in order to evaluate their cytotoxicity on LT2 endothelial cells. After 1 h of treatment with concentrations not higher than 10 mM, the number of cells was quantified by measuring DNA content. No significative decrease in the DNA amount was observed except for the dimethyl-β-CD at the highest tested concentration. |
| Keywords: | Cyclodextrins Cytotoxicity DNA assay Endothelial cells LT2 cell line |
| 本文献已被 SpringerLink 等数据库收录！ | |