Facile Synthesis of trans-3,4-Diol Derivatives of Substituted Chromans via Catalytic Epoxidation |
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摘 要: | PotassiumchannelopenersrpCOs)haveattractedconsiderableattentionbecauseofer4dencefortheirPOtentia-lvalueinthetrcatmentofhpertension,asthInaandurimpincontinence.'ASaresultofourinterestinthe1'asorelaxanteffeCtSofthechIomantwPOtaSsiumchanneloPeners,wehavp-nthesizedandevaluatedaseriesofdiesterderivahvesofSUbstitUtedtranS-3.4allhydroxycliromansurhjchhaVebeenshowntoekibitPOtentvasorelaxantaedvity.=mspaperdiscussesanovelnynthesisoftrans-3.4allolderivallvesofSUbintUtedchromansviacatalghcepokita…
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