A manganese-ferritin nanocomposite as an ultrasensitive T2 contrast agent |
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| Authors: | Sana Barindra Poh Chueh Loo Lim Sierin |
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| Institution: | Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore 637457. |
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| Abstract: | T(2) contrast is gaining importance in high field strength MRI. We report a strategy for developing a T(2) contrast agent from paramagnetic metal ions synthesized within an engineered protein cage. The manganese-ferritin nanocomposite showed high T(2) relaxivity indicating its potential as an ultrasensitive T(2) contrast agent. |
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