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Oxidation of Benzyl Alcohol with CuII and ZnII Complexes of the Phenoxyl Radical as a Model of the Reaction of Galactose Oxidase |
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| Authors: | Shinobu Itoh Masayasu Taki Shigehisa Takayama Shigenori Nagatomo Teizo Kitagawa Norio Sakurada Ryuichi Arakawa Shunichi Fukuzumi |
| Abstract: | Profound insights into the catalytic mechanism of galactose oxidase (GO) are offered by new models of the active form of the metalloenzyme. The important role of the CuII center in the oxidation of benzyl alcohol to benzaldehyde by the CuII–phenoxyl radical complex of ligand 1 has been revealed by comparison with the reactivity of the corresponding ZnII–phenoxyl radical complex; py=2-pyridyl. |
| Keywords: | Alcohols Copper Galactose oxidase Kinetics Phenoxyl complexes |