Integrated Chemical Process: One-Pot Aromatization of Cyclic Enones by the Double Elimination Methodology |
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Authors: | Akihiro Orita Jayamma Yaruva Junzo Otera |
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Abstract: | A variety of aromatic hydrocarbons bearing multiple alkyl substituents are accessible with perfect regiocontrol in a one-pot reaction starting from cyclohexenones and their aromatic analogues Eq. (1)]. The present methodology can be further extended to the synthesis of polycyclic aromatic hydrocarbons. The drawbacks encountered in the Friedel–Crafts reaction are resolved since the reaction proceeds under basic conditions. |
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Keywords: | Arenes Eliminations Enones Integrated chemical process One-pot reaction |
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