| Abstract: | Ion implantations into silicone rods were performed at 150 keV with doses ranging from 1 × 107 to 3 × 1017 ions/cm2. The antithrombogenicity was tested by the superior vena cava (SVC) indwelling method for two days in rats with 111In‐tropolone ‐ platelets, and by the inferior vena cava (IVC) indwelling method. Results of the SVC indwelling method showed that platelet accumulation on ion ‐ implanted specimens decreased. Macroscopic views of the ion‐implanted IVC specimens in dogs revealed little thrombus formation. In particular, SVC indwelling method revealed that O2+, K+ and Kr+ (1 × 1017 ions/cm2) implantation was most effective in reducing platelet accumulation. Copyright © 1999 John Wiley & Sons, Ltd. |
