Rapid acid hydrolysis of 5-aryl-3-(β-thiomorpholinoethyl)-1,2,4-oxadiazoles |
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Authors: | L A Kayukova M A Orazbaeva G I Gapparova K M Beketov A A Espenbetov M F Faskhutdinov B T Tashkhodjaev |
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Institution: | (1) A. B. Bekturov Institute of Chemical Sciences, 050010 Almaty, Republic of Kazakhstan;(2) S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, 100170, Republic of Uzbekistan |
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Abstract: | The acid hydrolysis of a series of 5-aryl-3-(β-thiomorpholinoethyl)-1,2,4-oxadiazoles gave substituted benzoic acids and 2-amino-8-thia-1-aza-5-azoniaspiro4.5]dec-1-ene
chloride hydrate, whose structure was demonstrated by spectral methods and X-ray diffraction structural analysis. |
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