| Effects of Lead on Temporal Response Properties of Retinal Ganglion Cells in Developing Rats |
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| 作者姓名： | 阮迪云 汤立新 赵晨 郭宇静 |
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| 作者单位： | Department of Biology，University of Science and Technology of China，Hefei 230026，PRC，Department of Biology，University of Science and Technology of China，Hefei 230026，PRC，Department of Biology，University of Science and Technology of China，Hefei 230026，PRC，Department of Biology，University of Science and Technology of China，Hefei 230026，PRC |
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| 基金项目： | Project supported by the National Natural Science Foundation of China. |
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| 摘 要： | Neonatal rats have taken in lead, during the period from their parturition to their weaning, from the milk of dams fed with water containing 0.2% lead acetate solutions. The alterations in the temporal response properties of retinal ganglion cells in adult rats (90 days) following the lead exposure at their developing stage have been studied. The results of this investigation demonstrate that the lead exposure in neonatal rats causes decreases in the optimal temporal frequency, bandwidth at half amplitude, temporal resolution and response phase of the retinal ganglion cells in adult rats. Compared with the sustained cells, the transient cells have a much greater alteration in temporal response properties.
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Effects of Lead on Temporal Response Properties of Retinal Ganglion Cells in Developing Rats |
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| RUAN Di-Yun TANG Li-XinZHAO Chen and GUO Yu-Jing.Effects of Lead on Temporal Response Properties of Retinal Ganglion Cells in Developing Rats[J].Science in China(Chemistry),1994(5). |
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| Authors: | RUAN Di-Yun TANG Li-XinZHAO Chen and GUO Yu-Jing |
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| Abstract: | Neonatal rats have taken in lead, during the period from their parturition to their weaning, from the milk of dams fed with water containing 0.2% lead acetate solutions. The alterations in the temporal response properties of retinal ganglion cells in adult rats (90 days) following the lead exposure at their developing stage have been studied. The results of this investigation demonstrate that the lead exposure in neonatal rats causes decreases in the optimal temporal frequency, bandwidth at half amplitude, temporal resolution and response phase of the retinal ganglion cells in adult rats. Compared with the sustained cells, the transient cells have a much greater alteration in temporal response properties. |
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| Keywords: | lead rat retinal ganglion cell temporal response properties |
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