Synthesis and spectral studies on palladium and platinum complexes with mono- and bidentate N-donor organic ligands and their interaction with calf thymus DNA in solution

Palladium(II) and platinum(II) complexes of the types PdLX₂, PdL₂X₂, PtL₂X₂ and the Pt(IV) complexes PtLX₂Y₂, PtL₂X₂Y′₂ (where L = mono- or bidentate organic ligand containing nitrogen donor atoms; X = Cl or Br; Y = Br and Y′ = OH) have been synthesized and characterized by elemental analysis, IR and X-ray photoelectron spectral data. The Pd 3d_5/2 binding energies indicate that the 8-aminoquinoline ligand is a better electron donor to the metal than other ligands studied. The Cl 2p_3/2 binding energies in the square planar pd(II) complexes are observed in the range 198.0–199.56 eV. The ν(PdCl) vibrations (ca 340 and 320 cm^?1) corresponding to two cis-Cl ligands were observed in the IR spectra. Binding through probably N-7 of the guanine residue and the phosphate oxygen in a chelate form is implied from UV difference spectral data.