Synthesis of β-(1-3)-D-glucan under high pressure

The polycondensation of 1,2-0-exo-cyanethylidene-4,6-di-0-acetyl-3-0-trityl--D-glucopyranose (I) was accomplished in the presence of triphenylmethylium perchlorate in CH₂Cl₂ under the pressure of 14 kbar. The reaction was performed in the frozen solution after the phasic transition of the system, and led to the product of polycondensation which, after the removal of the protecting groups, gave the exactly regio- and stereo-regular -(1–3)-D-glucan.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 9, pp. 2129–2132, September, 1990.