Nickel‐Catalyzed Asymmetric Transfer Hydrogenation of Hydrazones and Other Ketimines |
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| Authors: | Haiyan Xu Peng Yang Pratanphorn Chuanprasit Hajime Hirao Jianrong Zhou |
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| Institution: | Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371 (Singapore) |
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| Abstract: | We report the use of nickel catalysts for the catalytic transfer hydrogenation of hydrazones and other ketimines with formic acid. Strongly donating bisphosphines must be used to support the catalysts. As in enzymatic catalysis, attractive weak interactions may be important for stereochemical control by the nickel/binapine catalyst. |
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| Keywords: | asymmetric catalysis hydrazones hydride insertion nickel transfer hydrogenation |
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