Palladium‐Catalyzed Enantioselective CH Arylation for the Synthesis of P‐Stereogenic Compounds |
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| Authors: | Zi‐Qi Lin Wei‐Zhen Wang Shao‐Bai Yan Prof Dr Wei‐Liang Duan |
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| Institution: | State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032 (China) |
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| Abstract: | A palladium‐catalyzed enantioselective C? H arylation of N‐(o‐bromoaryl)‐diarylphosphinic amides is described for the synthesis of phosphorus compounds bearing a P‐stereogenic center. The method provides good enantioselectivities and high yields. The products were readily transformed into P‐chiral biphenyl monophosphine ligands. |
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| Keywords: | asymmetric catalysis C H activation chirality palladium P ligands |
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