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Research in the olfactory detection of chemical agents
Authors:EJ Poziomek  GL BoshartEV Crabtree  R DehnJM Green  DJ HoyRA Mackay  GT PryorH Stone  M Tanabe
Institution:Physical Research Laboratory, Edgewood Arsenal, Maryland 21010; and Stanford Research Institute, Menlo Park, California 94025 USA
Abstract:This paper describes in a review fashion research on the olfactory detection of various electrophiles including toxic organophosphorus compounds. The method involves rapid formation of an odoriferous alkyl isocyanide from reaction of the electrophile with N-alkylformamides. Concepts of using olfactory sensing and a colorimetric procedure as subjective and objective methods, respectively, for isocyanides are discussed.
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