Triterpene saponins with XOD inhibitory activity from the roots of Ilex pubescens |
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Authors: | Li Ping Lin Wei Qu Jing Yu Liang |
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Affiliation: | Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China |
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Abstract: | A new triterpene saponin with 28-nor-urs-12(13),18(17)-dien-3β-ol as aglycone,named ilexsaponin C(1) was isolated from the roots of Ilex pubescens,together with three known saponins 2,3 and 4.The structure of 1 was elucidated on the basis of spectral analysis including 1D and 2D NMR and HR-ESI-MS.Saponins 1 and 4 exhibited significant XOD inhibitory activity in the test. |
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Keywords: | Triterpene saponin Ilex pubescens Ilexsaponin C Xanthine oxidase |
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