Citrinin derivatives from the marine-derived fungus Penicillium citrinum |
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Authors: | Chen Li Liu Wei Hu Xiao Huang Kai Wu Jiu-Lin Zhang Qi-Qing |
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Affiliation: | Institute of Biomedical and Pharmaceutical Technology & College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou, P.R. China. |
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Abstract: | Three new citrinin derivatives, penicitrinols C, D, and E (1-3), along with two known compounds, citrinin (4) and decarboxydihydrocitrinone (5), were isolated from Penicillium citrinum. Their structures were determined by spectroscopic methods and X-ray diffraction analysis. Compounds 1 and 3 demonstrated weak cytotoxicity against the HL-60 cell line. |
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